Figure 6 | Scientific Reports

Figure 6

From: Glyoxalase 1-knockdown in human aortic endothelial cells – effect on the proteome and endothelial function estimates

Figure 6

Inflammation and endothelial dysfunction.

Expression of genes involved in inflammation and endothelial function (IL-6 (A), RAGE (B), MCP-1(C), sVCAM-1 (E)) were analysed on mRNA level (N = 3, n = 3). **p < 0.01, ****p < 0.0001 vs. WT25mM+NT-siRNA, respectively. $p < 0.05, $$$$p < 0.0001 vs. WT25mM. MCP-1 (D), sVCAM-1 (F), and sICAM-1 (G) were further analysed on protein level in the cell supernatant fractions via ELISA (N = 3, n = 3). ***p < 0.001, ****p < 0.0001 vs. WT25mM+NT-siRNA, $$$p < 0.001, $$$$p < 0.0001 vs. WT25mM.

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