Figure 4 | Scientific Reports

Figure 4

From: Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells

Figure 4

ERK MAPK pathway regulated autophagy activation in CSE-treated Beas-2B cells.

Cells were pretreated with U0126 (10 μM) or SB203580 (10 μM) before exposed to 6%CSE for 24 h. (A) Expressions of LC3I and LC3II were measured by Western Blot. (B) Densitometry was performed and the ratio of LC3II/I were calculated. Results are representative of three independent experiments. Values are expressed as mean ± SEM (n = 3). *P < 0.05 with respect to the control group; #P < 0.05 with respect to the CSE-exposed group.

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