Figure 7 | Scientific Reports

Figure 7

From: CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress

Figure 7

Mitochondria are targets for CXCL12 in oxidative stress control.

CXCL12 or the mitochondrial ROS scavenger Mito Tempo reduces Mitosox Red MFI in sorted LSK cells. Cells were treated with rotenone (5 μM) or vehicle for 1 hour in absence or presence of CXCL12 (10 ng/ml) or Mito Tempo (2 μM). Mean ± SEM of 3–7 independent experiments.

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