Figure 1 | Scientific Reports

Figure 1

From: Abnormal Hypermethylation of the VDAC2 Promoter is a Potential Cause of Idiopathic Asthenospermia in Men

Figure 1

The association between VDAC2 and methylation.

(A) Demethylation increases the expression of VDAC2. GC 2-spd cells were treated with 5, 10 and 15 μmol/L 5-Aza-CdR for 48 h. The expression of VDAC2 with 15 μmol/L dose 5-Aza-CdR was higher by threefold than that in the comparison group. (B) Strong promoter activity was detected by dual-luciferase reporter assay in the prognostic region −2000 bp to +1000 bp of VDAC2.

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