Figure 3 | Scientific Reports

Figure 3

From: Abnormal Hypermethylation of the VDAC2 Promoter is a Potential Cause of Idiopathic Asthenospermia in Men

Figure 3

Methylation patterns of VDAC2 (14 CpGs) in human sperm.

(A) Methylation patterns of VDAC2 promoter in normozoospermia. (B) Methylation patterns of the VDAC2 promoter in idiopathic asthenospermia. (C) Percentages of clones with four different methylation statuses of VDAC2 promoter. (D) Mean percentages of cytosine methylation in all 14 CpGs of VDAC2 promoter. NZ: normozoospermia; IAS: idiopathic asthenospermia; CpGs: methylated shown in black, unmethylated shown in white. Data are expressed as means ± SD (25 patients for the IAS group and 27 donors for the NZ group). Statistically significant differences from the control group (NZ) were represented with asterisks: *P < 0.05, **P < 0.01.

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