Figure 1
Scheme of experimentation – different topographies were fabricated and seeded with adipose-derived stem cells.
The influence of substrate topography, on cell fate is examined with live imaging of cells over 21 days and cell shape and differentiation were measured. Scanning electron micrographs of uncoated glass coverslip or flat topography, random topography and aligned topography are shown at the left of Fig. 1. The alignment of the nanotopography in aligned substrates is horizontal across the page – scale bars 1 μm.
