Table 1 Patient demographics and clinical characteristics of the Melbourne discovery cohort and the replication cohorts.
Discovery Cohort (Melbourne) (n = 297) | Replication Cohort (Nijmegen/Cologne/Montreal) (n = 376) | |
|---|---|---|
Sex | ||
Female | 181 (60.9%) | 214 (56.9%) |
Male | 116 (39.1%) | 162 (43.1%) |
Age (years), mean ± SD Range | 79.2 ± 7.1 (53–102) | 77.1 ± 7.4 (53–97) |
Baseline Visual Acuity (ETDRS letters), mean ± SD Range | 51.0 ± 17.5 (2–88) | 52.6 ± 18.0∞ (1–85) |
Type of lesion | ||
Predominantly Classic | 23% | 19.4% |
Non-Predominantly Classic | 77% | 69.7% |
Missing Data | 11% | 10.9% |
*+Size of CNV | ||
<2 optic-disc area | 44% | 24.5% |
>2 Optic-disc area | 29% | 51.3% |
Missing Data | 27% | 24.2% |
Number of Injections at 6 months, mean ± SD | 4.7 ± 1.3 | NA |
^Number of Responders/Non-responders | ||
3 Month | 84%/16% | 82%/18% |
6 Month | 79%/21% | 76%/24% |
