Table 3 Crude and adjusted ORs and confounders.

From: Chorioamnionitis appears not to be a Risk Factor for Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis

 

Study or subgroup

Crude OR (95% CI)

P

Adjusted OR (95% CI)

P

Confounders included in analysis

Clinical

Botet

0.799 (0.445–1.434)

0.452

0.705 (0.443–1.122)

0.140

GA

Garcia-Muñoz

1.417 (1.264–1.588)

0.000

0.830 (0.710–0.970)

0.019

GA, BW

Soraisham

1.544 (1.243–1.918)

0.000

0.750 (0.561–1.002)

0.052

GA, BW, delivery mode, ACS, maternal hypertension, 5 min Apgar

Clinical

1.383 (1.134–1.686)

0.001

0.802 (0.703–0.915)

0.001

 

Histological

Been

1.278 (0.784–2.082)

0.325

1.172 (0.537–2.560)

0.691

GA, SGA, sex, multiple birth, delivery mode, preeclampsia, PROM, ACS

Elimian

1.861(1.373–2.522)

0.000

1.060(0.740–1.519)

0.751

GA, BW, BW percentile, 5 min Apgar

Lau

2.318 (1.646–3.262)

0.000

2.218(1.552–3.170)

0.000

GA, BW, delivery mode, multiple births, ACS, maternal hypertension, SGA, 5?min Apgar <7, SNAP-II score, NTISS score

Miyazaki

1.209 (1.050–1.391)

0.008

0.830(0.698–0.987)

0.035

GA, BW, SGA, sex, maternal age, parity, diabetes, preeclampsia, PROM, NRFS, ACS, delivery mode

Mu

2.075 (0.673–6.396)

0.204

1.653 (0.510–5.358)

0.402

GA

Rocha

2.520(1.241–5.115)

0.011

0.900 (0.400–2.025)

0.799

GA, BW

Smit

2.245 (1.254–4.021)

0.007

0.979 (0.428–2.237)

0.960

GA, SGA, sex, multiple birth, delivery mode, preeclampsia, PROM, ACS

Hitti

5.000 (2.071–12.070)

0.000

1.500 (0.900–2.500)

0.120

BW

Histological

1.925 (1.416–2.616)

0.000

1.214(0.871–1.692)

0.252

 
 

Overall

1.524 (1.29–1.80)

0.000

0.849 (0.751–0.959)

0.009

 
  1. GA: Gestational age, BW: Birth weight, ACS: Antenatal corticosteroids, SGA: Small for GA, PROM: Premature rupture of membranes SNAP-II: Score for Neonatal Acute Physiology, PROM: Premature rupture of membranes, NTISS: Neonatal therapeutic intervention scoring system, NRFS: Non-reassuring fetal status.