Figure 8
Structural visualization and topology diagram of CcEstA.
The large α/β domain and small α domain of CcEstA are distinguished by different colors (light blue and light green, respectively). (A) Topology diagram of CcEstA. The catalytic triad residues are shown in red, and His328 in Motif III in blue. The dashed line between α8 and α9 represents a missing invisible region of electron density. (B) The overall structure of CcEstA is shown with a ribbon diagram. (C) Molecular surface of CcEstA. The substrate-binding pocket of CcEstA is shown at the center. Inside the pocket, the catalytic Ser and Tyr are shown in yellow and red, respectively. (D) Surface charge distribution of CcEstA. Blue and red regions indicate local positive and negative charge, respectively.
