Figure 4 | Scientific Reports

Figure 4

From: B- and T-lymphocyte number and function in HIV+/HIV− lymphoma patients treated with high-dose chemotherapy and autologous bone marrow transplantation

Figure 4

B-cell functional response.

The average number of in-vivo B-cell divisions (A), the percentage of cells in the final culture that divided at least once (B) and the average number of divisions after in-vitro stimulation (C) were evaluated in HIV+ (black dots) and HIV− patients (white squares) at the indicated time points and compared with that of HC (rhombi). Error bars represent the 95% confidence interval of the mean. Grey horizontal lines represent the highest and lowest values measured in HC. Two HIV+ and two HIV− patients were not analyzed for functional study for the lack of cells at the baseline time point. *Significant differences between HIV+ patients in comparison to HIV− patients at the indicated time-point. Single-headed dashed arrows: significant variation in respect to T0 in HIV− patients. HC: healthy controls; T0: before ASCT (baseline), T3, T6, T12, and T24: at 3, 6, 12, and 24 months after ASCT, respectively.

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