Figure 6 | Scientific Reports

Figure 6

From: B- and T-lymphocyte number and function in HIV+/HIV− lymphoma patients treated with high-dose chemotherapy and autologous bone marrow transplantation

Figure 6

T-cell functional response.

The percentage of CD4+ (A) and CD8+ (B) cells that divided at least once and the average number of divisions of CD4+ (C) and CD8+ (D) lymphocytes after in-vitro stimulation with PHA were evaluated in HIV+ (black dots) and HIV− (white squares) patients at the indicated time points and compared with that of HC (rhombus). Two HIV+ and two HIV− patients were not analyzed for functional studies due to the lack of cells at the basal time point. One data point for CD8+ cells divisions in HIV+ patients was considered a significant outlier and removed. Horizontal lines indicated significant differences between cell subsets of HIV+ patients and HIV− patients in comparison to control. HC: healthy controls; T0: before ASCT (baseline), T3, T6, T12, and T24: at 3, 6, 12, and 24 months after ASCT months after ASCT, respectively.

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