Figure 3 | Scientific Reports

Figure 3

From: Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells

Figure 3

PD potentiated apoptosis induced by MK2206 in NSCLC cells.

(A) After treated with indicated concentrations of MK2206 for 48 h with or without PD (10 μM), apoptotic cells were stained with Annexin V/PI and analyzed by flow cytometry. Results were shown as mean ± SD for three independent assays. *P < 0.05, **P < 0.01, and ***P < 0.001. (B) After treated with indicated concentrations of MK2206 for 48 h with or without PD (10 μM), the enzyme activities of caspase 3/7 were measured.

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