Figure 1

LD structure and significantly associated LD blocks based on two-stage data.
LD blocks in HTR1A are indicated by the shaded matrices, and significantly associated LD block 1 in the discovery stage (A) was confirmed in the replication stage (B); LD blocks in HTR5A are indicated by the shaded matrices, and significantly associated LD block 2 in the discovery stage (C) was also confirmed in the replication stage (D). The two associated SNPs (rs878567 and rs1800883) are marked by circles.