Table 4 Comparisons of executive function of 2 associated SNPs in patients and controls.
Subjects | SNP/Genotype | PE | NPE | TE | TCFC |
|---|---|---|---|---|---|
Schizophrenia patients | rs878567 (HTR1A) | ||||
GG | 31.52 (0.17) | 38.73 (0.10) | 70.24 (0.20) | 67.57 (0.11) | |
GA | 31.95 (0.26) | 38.50 (0.15) | 70.44 (0.30) | 67.55 (0.16) | |
AA | 32.85 (0.83) | 39.33 (0.48) | 72.18 (0.98) | 67.60 (0.51) | |
P-value | 0.139 | 0.179 | 0.144 | 0.992 | |
rs1800883 (HTR5A) | |||||
CC | 31.29 (0.28) | 38.66 (0.16) | 69.95 (0.33) | 67.47 (0.18) | |
CG | 31.52 (0.20) | 38.63 (0.12) | 70.15 (0.24) | 67.78 (0.12) | |
GG | 32.37 (0.27) | 38.79 (0.15) | 70.14 (0.32) | 67.24 (0.17) | |
P-value | 0.012 | 0.725 | 0.016 | 0.031 | |
non-GG | 31.44 (0.16) | 38.64 (0.10) | 70.08 (0.19) | 67.68 (0.10) | |
GG | 32.37 (0.27) | 38.79 (0.15) | 70.14 (0.32) | 67.24 (0.17) | |
P-value | 0.004 | 0.435 | 0.005 | 0.028 | |
Healthy controls | rs878567 (HTR1A) | ||||
GG | 5.630 (0.052) | 13.689 (0.062) | 19.319 (0.082) | 22.171 (0.105) | |
GA | 5.470 (0.074) | 13.713 (0.087) | 19.184 (0.115) | 21.898 (0.147) | |
AA | 5.822 (0.201) | 13.625 (0.236) | 19.447 (0.314) | 22.268 (0.401) | |
P-value | 0.104 | 0.932 | 0.548 | 0.285 | |
rs1800883 (HTR5A) | |||||
CC | 5.551 (0.08) | 13.727 (0.09) | 19.278 (0.12) | 22.140 (0.16) | |
CG | 5.584 (0.06) | 13.694 (0.07) | 19.278 (0.093) | 22.071 (0.12) | |
GG | 5.636 (0.09) | 13.653 (0.10) | 19.289 (0.14) | 22.057 (0.18) | |
P-value | 0.77 | 0.867 | 0.998 | 0.923 | |
