Figure 2
From: Remarkable alterations of Nav1.6 in reactive astrogliosis during epileptogenesis
Photomicrographs of Nav1.6 immunoreactivity in the hippocampus in KA-induced TLE rats and the control groups.
(A–F) Nav1.6-ir (red) is progressively increased in the ipsilateral hippocampus at 1 day, 7 days, 21 days, 63 days after SE, peaking at 21 days after SE compared with the contralateral side and the controls. (G) Nav1.6-ir (red) positive cells present morphological changes with the development of epilepsy. SO: stratum oriens; SR: stratum radiatum; SL: stratum lucidum; SP: stratum pyramidale.
