Figure 9
From: Remarkable alterations of Nav1.6 in reactive astrogliosis during epileptogenesis
Expression of Nav1.6 in the hippocampus in PTZ-kindled animals.
(A) Real-time PCR analysis for Nav1.6 expression in the hippocampus in PTZ-kindled animals and the control groups. Each column represents mean ± SEM of five animals in each group. *P < 0.05, **P < 0.01, significantly different from the control animals. (B–E) A small amount of Nav1.6-ir is observed in the stratum pyramidale in the hippocampus in PTZ-kindled animals and the controls. Nav1.6-ir (red) is not co-localized with GFAP-ir positive cells (green) both in the controls and PTZ-kindled rats (B,C). Nav1.6-ir (red) is located in NeuN-ir positive cells (green) both in the controls and PTZ-kindled rats (D,E).
