Figure 7
Peak current ACh concentration-response curves in the absence (●) or presence (■) of PhTX-343 at 1 μM for α4β2, α4β4, α3β2 and α3β4, 10 μM for α1β1γδ and 30 μM for α7.
Curves were fitted with Eq. 2 and EC50 values are given in Table 3. The grey symbols (
) show the % control response for each ACh concentration in the presence of PhTX-343. VH = −80 mV in all cases.
