Figure 6

In-vivo18F-FDG PET/MRI and ex-vivo14C-acetate uptake assay study for BAT amount and activity.
(A) Ex vivo14C-acetate uptake in BAT (n = 10/group). (B) Active iBAT volume evaluated by PET/MR imaging. (C) Longitudinal (left) and transversal (right) 18F-FDG PET/MR fused images and (D) SUVR of iBAT in euthyroid, hyperthyroid and hypothyroid mice. (D) Proportion of activated BAT (% of total BAT). Data are presented as mean and SEM (*p < 0.05, **p < 0.01, ***p < 0.001).