Figure 1 | Scientific Reports

Figure 1

From: The rodent malaria liver stage survives in the rapamycin-induced autophagosome of infected Hepa1–6 cells

Figure 1

P. y. yoelii sporozoite infection induces a selective autophagy-like process targeting EEFs.

After Hepa1-6 cells growing on a coverslip were incubated with P. y. yoelii 265BY-RFP sporozoites for the indicated time, the cells were stained with anti-LC3, anti-LAMP1 and DAPI and subjected to confocal microscopy. (A) A representative confocal microscopic image of EEFs in the autophagy-like vacuole at the indicated incubation time. (B) Percentage of EEFs in the autophagy-like vacuole at the indicated incubation time. (C) Percentage of LC3 and LAMP1 double-positive vesicles containing EEFs at the indicated time. All data are presented as the mean ± SD.

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