Table 1 Clinical characteristics of patients with pT3 UTUC.

From: Adjuvant radiotherapy for locally advanced upper tract urothelial carcinoma

 

No Adjuvant Radiotherapy (n = 158)

Adjuvant Radiotherapy (n = 40)

P value

Gender, n (%)

  

1.000

 Female

82 (51.9)

21 (52.5)

 

 Male

76 (48.1)

19 (47.5)

 

Age, yrs, median (range)

70.5 (23.6–91.6)

65.2 (39.5–82.9)

0.023

 Less than 68.6, n (%)

75 (47.5)

24 (60.0)

0.215

 68.6 or greater, n (%)

83 (52.5)

16 (40.0)

 

Current smoking status, n (%)

  

0.119

 No

139 (88.0)

31 (77.5)

 

 Yes

17 (10.7)

9 (22.5)

 

 Unknown

2 (1.3)

0 (0)

 

ASA score, n (%)

  

0.931

 1

3 (1.9)

1 (2.5)

 

 2

70 (44.3)

19 (47.5)

 

 3

84 (53.2)

20 (50.0)

 

 4

1 (0.6)

0 (0)

 

Recurrent bladder tumor, n (%)

41 (25.9)

8 (20.0)

0.540

Recurrent contralateral UTUC, n (%)

10 (6.3)

2 (5.0)

1.000

eGFR (mL/min/1.73 m2), median (range)

43.1 (0–86.5)

44.9 (0–77.4)

0.265

 Less than 60, n (%)

132 (83.5)

33 (82.5)

0.817

 60 or greater, n (%)

26 (16.5)

7 (17.5)

 

Tumor Grade, n (%)

  

0.125

 Low

11 (7.0)

0 (0)

 

 High

147 (93.0)

40 (100)

 

Lymphovascular invasion, n (%)

31 (19.6)

9 (22.5)

0.664

Carcinoma in situ, n (%)

20 (12.7)

6 (15.0)

0.793

Positive surgical margin, n (%)

5 (3.2)

4 (10.0)

0.084

  1. UTUC: upper tract urothelial carcinoma, ASA: American Society of Anesthesiologists, eGFR: estimated glomerular filtration rate.