Table 1 Relationships between miR-96-5p expression level and other SLE parameters and between miR-182-5p expression level and other SLE parameters.

From: Mesenchymal stem cell transplantation can restore lupus disease-associated miRNA expression and Th1/Th2 ratios in a murine model of SLE

Parameter

miR96-5p

miR182-5p

Pearson’s correlation coefficient

P value (two-tailed)

Pearson’s correlation coefficient

P value (two-tailed)

miR96-5p

1

—

0.960

<0.001

miR182-5p

0.960

<0.001

1

—

Spleen weight

0.766

0.001

0.753

0.001

Lymph node weight

0.732

0.001

0.708

0.002

Spleen weight/body weight

0.772

<0.001

0.750

0.001

Lymph node weight/body weight

0.718

0.002

0.693

0.003

BUN

0.135

0.619

0.051

0.850

Glomerular IgG deposition

0.606

0.013

0.621

0.010

Glomerular C3 deposition

0.915

<0.001

0.904

<0.001

Urine protein, 40 weeks of age

0.319

0.229

0.273

0.306

Urine creatinine, 40 weeks of age

0.224

0.403

0.393

0.132

Urine protein/creatinine, 40 weeks of age

0.260

0.332

0.164

0.544

Anti-dsDNA antibody, 40 weeks of age

0.734

0.001

0.631

0.009

CD138

0.930

<0.001

0.918

<0.001

ROR-γt+

−0.151

0.699

−0.182

0.638

T-bet+

0.659

0.054

0.699

0.036

GATA3+

−0.062

0.874

−0.052

0.894

CD4+CD25+

−0.651

0.057

−0.642

0.062

ROR-γt+ of CD4+ CD25+

0.143

0.713

0.008

0.984

Tbet+ of CD4+ CD25+

0.844

0.004

0.815

0.007

GATA+ of CD4+ CD25+

−0.114

0.770

−0.127

0.745

CD4+ CD25+ Foxp3+

−0.829

0.006

−0.804

0.009

CD4+ CD25+ ROR-γt+

−0.284

0.458

−0.396

0.291

CD4+ CD25+T-bet+

0.056

0.887

0.038

0.923

CD4+CD25+GATA3+

−0.210

0.588

−0.219

0.571

Treg/Th17

−0.392

0.297

−0.249

0.518

Th1/Th2

0.829

0.006

0.841

0.004

  1. Pearson’s correlations were used to evaluate the relationships miRNA expression levels and other SLE parameters. Correlations were defined as weak (<0.3), moderate (0.3–0.7), or strong (>0.7). SLE: systemic lupus erythematosus, BUN: blood urea nitrogen.
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