Table 1 Demographic characteristics of healthy volunteers and patients with liver cirrhosis.

From: Increased EMR2 expression on neutrophils correlates with disease severity and predicts overall mortality in cirrhotic patients

Parameters

Healthy Volunteers (n = 48)

Liver cirrhosis

Child A (n = 26)

Child B (n = 26)

Child C (n = 48)

P value

Male, n (%)

34 (70.8)

20 (76.9)

20 (76.9)

37 (77.1)

0.883

Age, M ± SD (years)

51.6 ± 10.7

55.8 ± 9.9

57.2 ± 14.9

53.5 ± 13.8

0.263

Etiology

    

0.656

 Alcohol

 

10 (38.5)

10 (38.5)

17 (35.4)

 

 HBV

 

12 (46.2)

8 (30.8)

21 (43.8)

 

 HCV

 

4 (15.4)

8 (30.8)

10 (20.8)

 

Child-Turcotte-Pugh score

 

5.1 ± 0.3

7.9 ± .0.7

12.2 ± 1.3

<0.001

MELD score

 

8.8 ± 4.7

12.3 ± 5.8

22.6 ± 10.7

<0.001

Bilirubin total (mg/dL)

0.90 ± 0.33

1.18 ± 0.42

2.39 ± 3.55

10.36 ± 10.58

<0.001

Albumin (g/dL)

4.69 ± 0.27

4.0 ± 0.6

3.1 ± 0.5

2.7 ± 0.4

<0.001

WBC* (×100/μl)

61.16 ± 14.14

59.94 ± 30.09

50.06 ± 26.58

66.38 ± 33.10

0.413

ANC* (×100/μl)

35.47 ± 10.83

38.22 ± 21.42

35.75 ± 21.68

47.47 ± 26.60

0.307

Platelets (×1000/μl)

230.06 ± 59.38

163.05 ± 97.15

84.18 ± 59.87

87.07 ± 66.16

<0.001

AST (U/L)

23.23 ± 9.92

64.25 ± 57.35

60.43 ± 51.97

92.00 ± 65.34

<0.001

ALT (U/L)

25.93 ± 12.51

47.62 ± 45.04

30.60 ± 17.55

48.96 ± 45.43

0.003

INR

1.03 ± 0.08

1.12 ± 0.11

1.38 ± 0.21

1.86 ± 0.79

<0.001

Cr (mg/dL)

0.94 ± 0.22

1.24 ± 1.25

1.31 ± 1.26

1.53 ± 1.31

0.011

EMR2 Neutrophil (MFI)

18.38 ± 7.74

23.74 ± 11.55

33.97 ± 18.00

39.89 ± 24.95

<0.001

  1. 48 healthy volunteers (34 male, 14 female; mean age: 51 ± 10 years old) and 100 cirrhotic patients (69 male, 23 female; mean age: 55 ± 13 years old: 26 patients in CTP A group, 26 patients in CTP B group, and 48 patients in CTP C group) were enrolled in this case-control cohort study. There were no differences among these groups in terms of gender, age, and etiologies. The white blood cell counts (WBC) and absolute neutrophil count (ANC) did not decrease significantly in these groups, too.
  2. *WBC, ANC: subjects without infections counted.
Back to article page