Figure 1 | Scientific Reports

Figure 1

From: Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species

Figure 1

SHK inhibits cell proliferation and induces cell death.

(a) Structure of shikonin (C16H16O5). (b) SHK induces cell death in GES-1, BGC-823 and SGC-7901 cells at 24 h as visualized by microscopy (100×, Scale bars: 50 μm). Cells were treated with increasing concentrations of SHK for 24 h (c) and different concentrations of SHK for different times (d,e,f) as indicated. Cell viability was determined by MTT assays. Values are presented as the mean ± SD of eight independent experiments for MTT and three independent experiments for flow cytometry. *P < 0.05, **P < 0.01.

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