Figure 7
SHK enhances the chemotherapeutic sensitivity of SGC-7901 gastric cancer cells.
(a) MTT assays were used to detect the chemotherapeutic effects of 5-Fu and Oxa alone or in combination with SHK (5 μM) 24 h after treatment. (b) Cell morphology was visualized by microscopy (100×, Scale bars: 50 μm), and cell death was detected by flow cytometry 24 h after treatment with 5-Fu (50 μg/ml) or Oxa (10 μM) alone or in combination with SHK (5 μM). (c) Intracellular ROS was detected by DCF probes at 6 h after treatment same as (b). (d) MMP was detected by flow cytometry using JC-1 12 h after treatment same as (b). Values are presented as the mean ± SD for three independent experiments. *P < 0.05, **P < 0.01.
