Figure 1
From: Four microRNAs Signature for Survival Prognosis in Colon Cancer using TCGA Data
Based on ROC curve cutoff point, miRNAs expression level were divided into two groups: high level expression group and low level expression group.
Upon the survival analysis, 4-miRNAs, which was significantly related with patient survival (Log-rank method, *p < 0.05). The high expression level of miR-148a, miR-26a-2 and miR-130a were significantly associated with poor clinical outcome. In miR-130a group, 5-year survival rate was 87.5% in low level group, only 56.3% in high level group (A). In miR-26a-2 and miR-148 group, 5-year survival rates were 78.3% and 67.9% in low level group respectively, only 42.8% and 45.2% in high level group (B,C). Reversely, in miR-103-1, 5-year survival rate was 68.7% in high level group, only 40.5% in low level group (D).
