Table 2 KEGG pathway analysis of predicted targets from the four miRNAs.
From: Four microRNAs Signature for Survival Prognosis in Colon Cancer using TCGA Data
Pathway | Count | Genes | p value |
|---|---|---|---|
hsa05214:Glioma | 8 | NRAS, SOS1, SOS2, TGFA, IGF1, PTEN, CALM2, SHC4 | 0.001 |
hsa04115:p53 signaling pathway | 7 | BID, ZMAT3, IGF1, PMAIP1, MDM4, GADD45A, PTEN | 0.002 |
hsa05200:Pathways in cancer | 14 | BID, NRAS, CCDC6, RET, SOS1, SOS2, PPARG, TGFBR2, MITF, SKP2, TGFA, IGF1, AXIN2, PTEN | 0.009 |
hsa04722:Neurotrophin signaling pathway | 8 | RPS6KA5, NRAS, ZNF274, SOS1, SOS2, PRKCD, CALM2, SHC4 | 0.009 |
hsa04910:Insulin signaling pathway | 8 | PRKAG3, NRAS, TSC1, SOS1, SOS2, RHOQ, CALM2, SHC4 | 0.014 |
hsa05213:Endometrial cancer | 5 | NRAS, SOS1, SOS2, AXIN2, PTEN | 0.017 |
hsa05216:Thyroid cancer | 4 | NRAS, CCDC6, RET, PPARG | 0.017 |
hsa04012:ErbB signaling pathway | 6 | NRAS, EREG, SOS1, SOS2, TGFA, SHC4 | 0.025 |
hsa05215:Prostate cancer | 6 | NRAS, SOS1, SOS2, TGFA, IGF1, PTEN | 0.027 |
hsa05220:Chronic myeloid leukemia | 5 | NRAS, SOS1, SOS2, TGFBR2, SHC4 | 0.054 |
