Figure 4 | Scientific Reports

Figure 4

From: The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function

Figure 4

Deletion of GluN2C subunit does not affect excitability of fast-spiking interneurons or pyramidal neurons in medial prefrontal cortex.

Whole-cell current clamp recording was performed from fast-spiking neurons and pyramidal neurons in layer V of medial prefrontal cortex. Current injection from −100 pA to 200 pA. No change in spike frequency was observed in either of the cell types due to deletion of GluN2C subunit. Other intrinsic properties and action potential characteristics were also unchanged (Table 1).

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