Table 1 Baseline characteristics of included patients who received more than three intravitreal conbercept injections for AMD and DME.

From: Changes in Retinal Nerve Fiber Layer Thickness after Multiple Injections of Novel VEGF Decoy Receptor Conbercept for Various Retinal Diseases

 

Total

AMD

DME

Patient (eyes)

49 (98)

38 (72)

11 (22)

Injection/Non-injection (eyes)

49/49

38/38

11/11

Mean age

66 ± 9

69 ± 7

57 ± 9

Sex (male:female)

32:17

25:13

7:4

 

Injection/Non-injection (p)

Injection/Non-injection (p)

Injection/Non-injection (p)

Baseline IOP (mmHg)

15.3 ± 2.8/15.9 ± 2.9 (0.301)

15.2 ± 2.9/15.8 ± 3.0 (0.357)

15.6 ± 2.5/16.1 ± 2.9 (0.658)

Baseline RNFL thickness (μm)

108.9 ± 24.0/109.9 ± 31.4 (0.863)

101.9 ± 13.8/101.3 ± 11.7 (0.823)

133.0 ± 35.0/139.6 ± 54.6 (0.738)

  1. AMD: age-related macular degeneration.
  2. DME: diabetic macular edema.
  3. IOP: intraocular pressure.
  4. RNFL: retinal nerve fiber layer.