Figure 9
NEU1 structural model and localization of the two potential TM domains.
(A) Top and (B) side view projections of the homology-based NEU1 model. Beta-sheets are shown in yellow, alpha-helices in red and loops in green for the “extracellular” part (between TM domains). Potential TM domains are colored in cyan, and the N- and C-terminal parts are colored in gray. Residues that may form catalytic center (determined by similarity) are shown in magenta for the “extracellular” part and in blue for N- and C-terminal part.
