Figure 2
From: Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians
In-depth analyses of transcriptome features characterizing CD4+ T cell during the aging process.
Illustration of gene expression patterns and corresponding biological theme enrichments for each of the ten gene clusters. The patterns of gene expression in 0-year (NB), 40-year (MA) and 90-year (LL) with green to red blocks, symbolizing relative expression levels corresponding to the scale bar at the bottom. Various biological annotations were mined to determine enrichments of biological relevance, as highlighted by GO analysis for functional enrichments (P-values < 0.05), motifs of JASPAR conserved transcription factor binding sites for regulatory enrichments (P-values < 0.05), and Online Mendelian Inheritance in Man (OMIM) disorder-gene association information for disorder enrichments (P-values < 0.05).
