Figure 7
From: Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians
Integrated analysis of DMGs and differentially expressed genes (DEGs) in the database of WGCNA models.
Unsupervised hierarchical clustering heatmap of hypermethylated and down-regulated genes or hypomethylated and up-regulated genes across CD4+ T cell samples distinguished MA from NB individuals (A) and LL from MA individuals (B). Red and green indicate high and low expression, and yellow and blue indicate hyper- and hypo-methylation, respectively. Gene symbols are indicated on the right. Red, blue and green pentagrams represent genes within the GenAge, GenDR and longevityMap from HAGR databases, respectively. Red and green represent relative expression levels corresponding to the scale bar at the bottom, yellow and blue represent relative methylation levels corresponding to the scale bar at the bottom.
