Figure 3
From: Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4
Absence of functional effects of KCNE3L and KCNE4L on human HCN1.
(A) Exemplar current traces recorded from Xenopus oocytes expressing HCN1 alone (n = 13) or with KCNE3L (E3L; n = 17), or KCNE4L (E4L; n = 15). Insets: left, scale bars; right, Voltage clamp protocol. Zero current level indicated by dashed line. (B) Mean ± SEM instantaneous current/voltage relationship for currents as in panel A; n values as in (A). (C) Mean ± SEM peak current/voltage relationship for currents as in panel A; n values as in panel A. (D) Mean ± SEM normalized G/V relationship measured at beginning of tail pulse for currents as in panel A; n values as in panel A.
