Table 4 Group differences in brain metabolite creatine ratios in the anterior cingulate cortex.

From: Elderly patients have an altered gut-brain axis regardless of the presence of cirrhosis

Metabolite creatine ratios

Based on underlying disease

Based on neuropsychological division

Non-cirrhotic

Cirrhosis

Unimpaired

Amnestic type

Amnestic+ Non-amnestic type

MyoinositoI

0.794 ± 0.08

0.593 ± 0.19‡‡

0.727 ± 0.15

0.824 ± 0.10

0.611 ± 0.19†

N-Acetyl Aspartate

1.303 ± 0.07

1.222 ± 0.12‡

1.294 ± 0.11*

1.266 ± 0.09

1.173 ± 0.09††

Glutamate+ Glutamine

1.812 ± 0.25

2.105 ± 0.47‡

1.955 ± 0.30

1.796 ± 0.29

1.897 ± 0.57

  1. ‡p < 0.05, ‡‡p < 0.01 between cirrhotic and non-cirrhotic, *p < 0.05, **p < 0.01. Unimpaired vs. amnestic + non-amnestic type; †p < 0.05, ††p < 0.01 amnestic vs. amnestic + non−amnestic type.
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