Figure 4
From: c-MET as a Potential Therapeutic Target in Ovarian Clear Cell Carcinoma

SU11274 inhibited the expression of c-MET and downstream signaling proteins in ES2 cells.
Based on Western blots, phospho-c-MET and phosphorylation of downstream signaling proteins including p-Akt and p-Erk were decreased by treatment with SU11274 in a dose-dependent manner. Strips corresponding to each of the proteins shown are cropped from different blots run under the same experimental conditions. The original blots were attached as Supplementary Figure 2.