Table 1 Characteristics of the five Salmonella enterica isolates carrying mcr-1.

Strain^a	Colistin MIC	Other resistant profile^b	Resistance gene(s)^b	Plasmid
Strain^a	Colistin MIC	Other resistant profile^b	Resistance gene(s)^b	Replicon type^b	Size of plasmid harbouring mcr-1 (kb)
S01	16	OLA, CIP, NAL, AMP, STR, GEN, FFC, TET, SMZ/TMP	mcr-1, oqxAB, aac(6′)-Ib-cr, floR	HI2	~190
GDS78	16	OLA, NAL, AMP, STR, GEN, FFC, TET, SMZ/TMP	mcr-1, aac(6′)-Ib-cr	HI2, I2, FIB, FII	~70
GDS79	16	OLA, NAL, AMP, STR, GEN, FFC, TET, SMZ/TMP	mcr-1, oqxAB, aac(6′)-Ib-cr, floR	HI2, I2, FIB, FII	~70
GDS82	16	OLA, NAL, AMP, STR, GEN, FFC, TET, SMZ/TMP	mcr-1, oqxAB, aac(6′)-Ib-cr, floR	HI2, I2, FIB, FII	~70
GDS141	16	OLA, NAL, AMP, STR, GEN, FFC, TET, SMZ/TMP	mcr-1, oqxAB, aac(6′)-Ib-cr, floR	HI2, I2, FIB, FII	~70

^aIsolates from which the mcr-1 gene can be transferred to the recipient by conjugation are underlined.
^bAMP, cefotaxime; STR, streptomycin; GEN, gentamicin; FFC, florfenicol; OLA, olaquindox; CIP, ciprofloxacin; NAL, nalidixic acid; TET, tetracycline; SMZ/TMP, trimethoprim/sulfamethoxazole. The antimicrobial susceptibility results were interpreted according to breakpoint of CLSI (M100-S25), except that florfenicol (≥32 μg/mL) was interpreted according to breakpoint of veterinary CLSI (VET01-A4/VET01-S3). All isolates were susceptible to amikacin, cefotaxime, cefoxitin, fosfomycin, and meropenem. Resistance phenotypes, genes and plasmids transferred to the recipient by conjugation are underlined.

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