Table 1 Helicity measurements for peptides with different sequences and molar ellipticities ([θ]/deg.cm².dmol⁻¹.residue⁻¹)³⁷.

Peptide	Sequence	[θ]₂₁₅	[θ]₂₀₇	[θ]₁₉₀	[θ]₂₁₅/[θ]₂₀₇	Helicity(%)
(R)-15B	Ac-c(1,5)-[X5AAAC(O)]-NH₂	−14351	−14763	24129	0.97	100
(R)-19B	Ac-c(1,5)-[X5AIAC(O)]-NH₂	−12334	−14211	25560	0.88	86
(R)-20B	Ac-c(1,5)-[X5AGAC(O)]-NH₂	−7839	−7731	9570	1.01	54
(R)-21B	Ac-c(1,5)-[X5AQAC(O)]-NH₂	−13358	−14886	27175	0.91	93
(R)-22B	Ac-c(1,5)-[X5AFAC(O)]-NH₂	−13235	−13379	25940	0.96	92
(R)-23B	Ac-c(1,5)-[X5ASAC(O)]-NH₂	−19357	−10950	1610	0.85	65
(R)-24B	Ac-c(1,5)-[X5KAEC(O)]-NH₂	−4497	−5552	1975	0.81	31

CD spectroscopy was performed in 10 mM PBS (pH = 7.4, 25 °C). [θ] was calculated according to literature³⁵; (R)-15B’s helicity was set to 100%, and the helicity of the other peptides were calculated by [θ]₂₁₅/[θ]₂₁₅(15B).

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