Figure 2 | Scientific Reports

Figure 2

From: Gut microbiota from metabolic disease-resistant, macrophage-specific RIP140 knockdown mice improves metabolic phenotype and gastrointestinal integrity

Figure 2

FMT transfers gut microbiota from donor to recipient.

(A) A scheme showing FMT experiment. (B) Left: Unweighted UniFrac based PCoA from RIP140mϕKD mice receiving FMT from WT (WT → KD) mice. Right: Unweighted UniFrac based PCoA from WT mice receiving FMT from RIP140mϕKD (KD → WT) mice. (C) Left panel: KD microbiome index in RIP140mϕKD mice receiving FMT from WT (WT → KD) mice. Right panel: KD microbiome index in WT mice receiving FMT from RIP140mϕKD (KD → WT) mice. (D) Representative pie chart of Bayesian source-tracking analysis of taxonomy, predicted metagenome and predicted GH of WT → KD mice post FMT 4 weeks (left panel) and KD → WT mice post FMT 4 weeks (right panel). Source contributions were averaged across samples within the population. WT → WT: WT receiving WT, KD → WT: WT receiving KD, WT → KD: KD receiving WT and KD → KD: KD receiving KD.

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