Figure 5
From: Identification of a CD133−CD55− population functions as a fetal common skeletal progenitor
CD133−CD55− common progenitors generated ectopic BM niche through endochondral differentiation.
KC grafts derived from CD133−CD55− progenitors were harvested at time indicated after transplantation. (A) Representative brightfield images (upper panel) and pentachrome stained sections (middle panel; yellow = osteoid, blue = cartilage) of KC grafts. The sections of adult limb bone and kidney were shown as control (lower panel). (B) Time course study of hematopoietic components during ectopic niche formation. Representative FACS profiles of HSC (CD45+Lineage-c-Kit+Sca1+) frequency that were pre-gated for live, CD45+lineage- cells.
