Figure 2

Interfaces of IgL1-2 dimerization.

(A) Residues that participate in homophilic interaction are plotted and displayed in 2D with DIMPLOT of the LigPlot plus suite³⁵. Protein side chains primarily involved in hydrophilic interaction are shown as ball-and-stick. Red, blue, black balls represent oxygen, nitrogen and carbon atoms respectively. Green dotted lines labeled with distances indicate hydrogen bonds. Non-bonded residues contributing to hydrophobic interactions are shown as spoked arcs. Oxford-blue dotted lines embrace residues located at the same IgL domains. Interface2 (in between IgL2-B and IgL1-A) and Interface1 (in between IgL1-B and IgL2-A) correspond to (B) and (C) revealing 3D representation of hydrogen bonds processed by Chimera. Chain A and B are colored in corn flower blue and hot pink respectively. O (red) and N (blue) atoms that contribute to hydrogen bonds are linked by dotted lines (dark blue) with distance labels.