Table 1 Comparison of the cytotoxicities of BAs between hiHeps and PHHs based on MTT assay.
BAs | HiHeps (IC50, μM) | PHHs (IC50, μM) |
|---|---|---|
Unconjugated BAs | ||
CA | 2207 | 1745 |
CDCA | 341.1 | 249.2 |
DCA | 314.9 | 237.3 |
LCA | 168.4 | 679.2 |
Conjugated BAs | ||
GCA | 4328 | 775.8 |
TCA | 998.6 | 1144 |
GCDCA | 1073 | 374.2 |
TCDCA | 1224 | 537 |