Figure 6 | Scientific Reports

Figure 6

From: Sexual dimorphic function of IL-17 in salivary gland dysfunction of the C57BL/6.NOD-Aec1Aec2 model of Sjögren’s syndrome

Figure 6

Sexual dimorphic effect of IL-17 on sera Th2 cytokines.

IL-5, IL-13, and IL-6 were decreased in females, and IL-4 and IL-10 were reduced in both sexes. Sera of mice (B6 F, n = 5; B6 M, n = 4; B6.Il17−/− F, n = 3; B6.Il17−/− M, n = 4; B6.NOD-Aec1Aec2 F, n = 14; B6.NOD-Aec1Aec2 M, n = 4; B6.NOD-Aec1Aec2.Il17−/− F, n = 3; B6.NOD-Aec1Aec2.Il17−/− M, n = 5) were analyzed using BioRad Bio-Plex manager. Graphs were generated using one-tailed Mann-Whitney t-tests in GraphPad, *p < 0.05 and ***p < 0.001.

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