Table 1 Focus score of the salivary glands.

From: Sexual dimorphic function of IL-17 in salivary gland dysfunction of the C57BL/6.NOD-Aec1Aec2 model of Sjögren’s syndrome

Strains

Sex (n)

Mean age (weeks)

Focus score

B6

M (10)

31.00 ± 0.00a

0.400 ± 0.163a

F (13)

30.08 ± 0.29

0.385 ± 0.140

B6.Il17−/−

M (4)

32.00 ± 0.00

0.500 ± 0.211

F (6)

34.00 ± 0.00

0.333 ± 0.500

B6.NOD-Aec1Aec2

M (8)

32.50 ± 0.57

1.250 ± 0.313b

F (21)

31.00 ± 1.54

1.619 ± 0.381b

B6.NOD-Aec1Aec2.Il17−/−

M (8)

28.00 ± 0.38

1.000 ± 0.267c

F (7)

35.71 ± 2.12

0.714 ± 0.286d

  1. *p < 0.5, **p < 0.01.
  2. aMean ± standard error.
  3. bB6.NOD-Aec1Aec2 males/females vs B6, B6.Il17−/− males/female(*).
  4. cB6.NOD-Aec1Aec2 males vs B6.NOD-Aec1Aec2.Il17−/− males (NS: not significant).
  5. dB6.NOD-Aec1Aec2 females vs B6 (**), B6.Il17−/− (**), B6.NOD-Aec1Aec2.Il17−/−(*) females.