Figure 5
Knockdown of STMN1 in J7 represses xenograft tumor growth.
(A) Subcutaneous injection of J7-shSTMN1 cells in nude mice. J7-shSTMN1 was generated from the pooled lentivirus (shSTMN1#37 and shSTMN1#94, 1:1). Briefly, 1*106 cells were suspended in 150 μl of PBS and injected into dorsal skin of mice. Two weeks later, visible tumor size was measured for 3 weeks (B). The mice were finally sacrificed at 5 weeks, and xenograft tumors were dissected (C) and weighed (D) (***P < 0.001; **P < 0.01 n = 4). Error bars, s.e.m.
