Table 1 List of bacterial mutants that enhance dauer formation.
From: A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans
Gene Knockout | Brief Description | Func. Group | Mean(%)a | ±SEb | nc | p-Value d |
|---|---|---|---|---|---|---|
K-12 | Control | / | 12.6 | 1.5 | 231 | / |
moaD | molybdopterin synthase, small subunit | MET | 81.9 | 3.2 | 117 | <0.0001 |
JW09292 | zapC: cell division factor, localises to the cytokinetics ring | OTR | 79.0 | 2.6 | 309 | <0.0001 |
fdoG | α subunit of formate dehydrogenase O | MET | 77.7 | 0.9 | 63 | <0.0001 |
JW1330 | abgT; predicted cryptic aminobenzoyl-glutamate transporter | MET | 72.1 | 3.5 | 222 | <0.0001 |
Lar | Rac prophae: restriction alleviation protein | OTR | 70.2 | 2.0 | 145 | <0.0001 |
panE | 2-dehydropantoate reductase, NADPH-specific | MET | 68.6 | 3.8 | 98 | <0.0001 |
mdoH | glucan biosynthesis: glycosyl transferase | CEB | 67.5 | 7.4 | 96.0 | 0.00 |
yjgB | predicted alcohol dehydrogenase, Zn-dependent and NAD(P)-binding | UNK | 67.5 | 3.3 | 180 | <0.0001 |
elaA | predicted acyltransferase, Zn- dependent and NAD(P)-binding | UNK | 66.7 | 3.2 | 207 | <0.0001 |
kdpB | potassium translocating ATPase, subunit B | ITM | 66.4 | 17.5 | 103 | 0.04 |
dcuC | anaerobic C4-dicarboxylate transport | MET | 65.2 | 1.6 | 186 | <0.0001 |
mutS | methyl-directed mismatch repair protein | DNA | 64.4 | 3.6 | 209 | <0.0001 |
htrG | predicted signal transduction protein (SH3 domain) | UNK | 64.3 | 5.4 | 194 | <0.0001 |
dhaH | fused predicted dihydroxyacetone-specific PTS enzymes: HPr component | MET | 63.4 | 11.4 | 63 | 0.01 |
rimK | ribosomal protein S6 modification protein | TRN | 62.8 | 3.3 | 72 | <0.0001 |
gloB | predicted hydroxyacylglutathione hydrolase | MET | 62.6 | 8.6 | 95.0 | 0.00 |
clpX | ATPase and specificity subunit of ClpX-ClcP ATP-dependent serine protease | TRN | 62.4 | 2.3 | 175 | <0.0001 |
tufa | protein chain elongation factor EF-Tu (duplicate of tuFB) | TRN | 60.7 | 3.0 | 69 | <0.0001 |
ybeA | 23S rRNA mψ1915 methyltranferase | OTR | 60.2 | 7.6 | 250 | 0.00 |
JW0632 | ybeB; predicted protein | UNK | 58.7 | 6.4 | 190 | 0.00 |
rfaD | ADP-L-glycero-D-mannoheptose-6-epimerase | CEB | 58.3 | 5.0 | 146 | <0.0001 |
yjiK | conserved protein | UNK | 56.4 | 5.4 | 151 | 0.00 |
fdoH | formate dehydrogenase-O, Fe-S subunit | MET | 56.0 | 10.7 | 65 | 0.02 |
yncA | predicted acyltransferase with acyl-CoA N-acyltransferase domain | CEB | 55.8 | 9.5 | 135 | 0.01 |
fepB | iron-enterbactin transporter subunit | ITM | 53.2 | 10.3 | 309 | 0.01 |
hsdS | specificity detereminant for hsdM and hsdR | DNA | 52.3 | 6.6 | 188 | 0.00 |
ygiQ | conserved protein | UNK | 51.0 | 9.2 | 63 | 0.01 |
Ung | iron-enterbactin transporter subunit | DNA | 50.6 | 11.6 | 70 | 0.03 |
hdfR | DNA-binding transcriptional regulator | TRX | 50.4 | 16.3 | 200 | 0.08 |
yjbD | conserved protein | UNK | 49.2 | 4.0 | 180 | 0.00 |
fepC | iron-enterbactin transporter subunit | ITM | 47.8 | 4.9 | 142 | 0.00 |
hypE | carbomoyl phosphate phosphatase, hydrogenase 3 maturation protein | TRN | 45.2 | 7.4 | 105 | 0.01 |
JW5726 | phnl, phnH; carbon-phosphorus lyase complex subunit | ITM | 43.5 | 4.2 | 112 | 0.00 |
ydhF | predicted oxidoreductase | UNK | 43.1 | 6.0 | 145 | 0.01 |
yqeH | conserved protein with bipartite regulator domain | TRX | 42.1 | 4.4 | 117 | 0.00 |
yjgN | conserved inner membrane protein | UNK | 41.4 | 4.8 | 97 | 0.00 |
JW1321.5 | Unknown | UNK | 40.0 | 5.7 | 236 | 0.01 |
cyaA | adenylate cyclase | OTR | 39.6 | 7.5 | 66.0 | 0.02 |
moaE | molybdopterin synthase, small subunit | MET | 38.3 | 7.7 | 82 | 0.03 |
sufA | Fe-S cluster assembly protein | MET | 37.6 | 5.1 | 229 | 0.01 |
sufE | sulphur acceptor protein | MET | 36.6 | 5.1 | 211 | 0.01 |
yggX | protein that protects iron-sulfur proteins against oxidative damage | TRN | 36.1 | 8.1 | 352 | 0.05 |
yheM | predicted intracellular sulfur oxidation protein | ITM | 36.0 | 2.8 | 208 | 0.00 |
yedR | predicted inner membrane protein | UNK | 33.5 | 8.1 | 294 | 0.07 |
fepG | iron-enterbactin transporter subunit | ITM | 32.3 | 6.8 | 195 | 0.03 |
yicM | purine ribonucleoside exporter | MET | 32.2 | 9.0 | 187 | 0.10 |
dmsC | dimethyl sulfoxide reductase, anaerobic, subunit C | MET | 32.1 | 1.8 | 111 | 0.00 |
yjgX | KpLE2 phage-like element; predicted protein (pseudogene) | UNK | 31.8 | 4.8 | 181 | 0.02 |
yrfD | predicted pilus assembly protein | MET | 31.6 | 4.9 | 195 | 0.02 |
srlA | glucitol/sorbitol -specific enzyme IIC component of PTS | MET | 30.6 | 4.0 | 323 | 0.01 |
pepA | aminopeptidase A, a cyteinylglycinase | MET | 29.8 | 2.6 | 216 | 0.00 |
yfaS | predicted protein (pseudogene) | UNK | 29.7 | 4.5 | 223 | <0.0001 |
Yjhc | KpLE2 phage-like element; predicted oxidoreducatse | UNK | 29.7 | 1.6 | 247.0 | <0.001 |
tolA | membrane anchored protein involved in colicin uptake | CEB | 29.2 | 3.8 | 186 | 0.02 |
ygjQ | predicted thioredoxin-like | UNK | 28.6 | 1.7 | 252 | 0.00 |
yqjH | predicted siderophore interacting protein | ITM | 28.3 | 1.0 | 367 | <0.0001 |
