Figure 3 | Scientific Reports

Figure 3

From: Changes in hippocampal AMPA receptors and cognitive impairments in chronic ketamine addiction models: another understanding of ketamine CNS toxicity

Figure 3

Changes of hippocampal membrane GluA1, p-S845 and p-S831 protein levels after three months of ketamine administration in the groups of Control 1, K1 30 mg/kg and K1 60 mg/kg as reveled by Western blot.

(a) Changes of hippocampal membrane GluA1 after three months of administration paradigm in three groups. (b) Significant increase of p-S831 expression levels were seen in the group of K1 60 mg/kg comparing with Control 1 (*p < 0.05). (c) Significant increase of p-S845 expression levels were seen in the group of K1 60 mg/kg comparing with control 1 and K1 30 mg/kg (*p < 0.05).

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