Figure 4 | Scientific Reports

Figure 4

From: Changes in hippocampal AMPA receptors and cognitive impairments in chronic ketamine addiction models: another understanding of ketamine CNS toxicity

Figure 4

Changes of hippocampal membrane GluA1, p-S845 and p-S831 protein levels after six months of ketamine administration in the groups of Control 2, K2 30 mg/kg and K2 60 mg/kg as reveled by Western blot.

(a) Significant decline of hippocampal membrane GluA1 expression levels were observed in K2 60 mg/kg comparing with Control 2 (*p < 0.05). (b) Significant decline of p-S831 were seen in K2 60 mg/kg comparing with Control 2 (*p < 0.05). (c) Significant decrease of p-S845 expression levels were seen in K2 30 mg/kg and K2 60 mg/kg comparing with Control 2 (*p < 0.05).

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