Figure 5 | Scientific Reports

Figure 5

From: Changes in hippocampal AMPA receptors and cognitive impairments in chronic ketamine addiction models: another understanding of ketamine CNS toxicity

Figure 5

Changes of the hippocampal membrane NR1 protein levels after three and six months of ketamine administration as reveled by Western blot.

(a) Significant decline of hippocampal membrane NR1 protein levels were observed in K1 60 mg/kg after three months of administration paradigm comparing with the group of Control 1 (*p < 0.05). (b) Significant decline of NR1 protein levels were seen in the group of K2 60 mg/kg comparing with the group of Control 2 and K2 30 mg/kg respectively (*p < 0.05, **p < 0.01).

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