Figure 2

Cine-strain estimation with in-house developed tissue deformation-tracking software.
Schematic illustration of deforming a target image to a reference image using a b-spline deformable registration method. Myocardial strain is calculated from the estimated deformation fields. The similarity measurement is defined as the sum of squared differences in pixel intensity between the two images, the deformation transformation between the target and the reference images is modeled with uniform cubic b-splines.