Table 1 Demographic and clinical baseline characteristics of 99 children with intra-thoracic TB and samples analyzed for transcriptional biomarkers (dcRT-MLPA).

Sociodemographics and medical history

 Gender

Male (n)

 Age

mean age in months (St.dev)

≤5 years (n)

>5 to ≤10 years (n)

>10 to 16 years (n)

 Known contact with TB patient (n)

 BCG vaccination

Yes (n)

No (n)

Not known (n)

Symptoms

 Cough ≥2 weeks (n)

 Fever (n)

 Weight loss (n)

 Loss of appetite (n)

Anthropometric data

 Body Mass Index Z-score, mean (St.dev)

 Weight-for-age Z-score, mean (St.dev)

Diagnosis and treatment

 Smear positivityˇ (n)

 Mtb-culture positive° (n)

 NTM culture positive^a (n)

 Finding on Chest X-ray

uncomplicated LN disease (n)

LN disease with collapse (n)

progressive primary disease (n)

primary pulmonary complex (n)

miliary TB (n)

pleural effusion (n)

cavitation disease (n)

calcification (n)

 Lymph node swelling (n)

 Tuberculin Skin Test

mean in mm (St.dev)

≥10 mm (n)

 QuantiFERON Gold In-tube

Positive (n)

Negative (n)

Indeterminate (n)

 Anti-tuberculosis treatment

Category 1 ^b (n)

Category 3 ^c (n)

 Micronutrient supplement

Micronutrients and Zinc (n)

Micronutrients (n)

Zinc (n)

Placebo (n)