Figure 6
From: STRAP Acts as a Scaffolding Protein in Controlling the TLR2/4 Signaling Pathway
Model of STRAP-mediated NF-κB activation in the TLR signaling pathway.
Following TLR stimulation, STRAP interacts with signaling regulators (TAK1, IKKα, and p65) as a scaffold protein in the early phase, and enters the nucleus in the late phase of TLR signaling to activate NF-κB-dependent genes.
